Y. Eugene Chen, MD, Ph.D

Frederick Huetwell Professor of Cardiovascular Medicine

Professor of Internal Medicine, Cardiac Surgery, Physiology, Pharmacology and Medicinal Chemistry

Vice Chair for Basic and Translational Research at Cardiac Surgery 

Director, Center for Advanced Models for Translational Sciences and Therapeutics

University of Michigan

NCRC Bld 26, Rm 361S

2800 Plymouth Rd

Ann Arbor, MI  48109-2800

Phone:  734-647-5742

Email:  echenum@umich.edu

Website: https://camtrast.med.umich.edu/

 

Dr. Chen is an endowed Frederick Huetwell Professor of Cardiovascular Medicine, Professor of Cardiac Surgery, Physiology, Pharmacology and Medicinal Chemistry, and Vice-Chair for Basic and Translational Research, Department of Cardiac Surgery at the University of Michigan (UM). The long-term goal of Dr. Chen’s laboratory is to stimulate bench-to-bedside research that sheds light on molecular mechanisms underlying the development and progression of metabolic and cardiovascular diseases. Dr. Chen cloned Exendin 4 (BYETTA), facilitating GLP1 drug development. He discovered the mechanisms of nitro-fatty acids, novel anti-inflammatory signaling molecules, currently in phase 2 clinical trials. Recently he embarked in successful integration of human genetic discoveries with translational research. Dr. Chen is the Founding Director of the Center for Advanced Models for Translational Sciences and Therapeutics at UM since July 2012, which generates gene-targeted (knockout and knockin) and transgenic rabbits/pigs for human disease models.